The Role of Hormones in Female Sexual Desire

You deserve a product that has been clinically studied, carefully formulated, and made to the highest safety and quality standards.

• A GP is the first point of contact for discussing sexual health concerns in the UK.
• They may conduct blood tests to check hormone levels (e.g., testosterone, estrogen).
• A full medical and psychological history is essential for an accurate diagnosis.
• GPs can refer patients to a specialist clinic, like a urogynaecology or sexual health service.
• Specialists may work in NHS hospitals or private practices.
• The British Society for Sexual Medicine provides guidelines for healthcare professionals.
• A diagnosis often involves ruling out other medical and relationship issues first.

With DARE to PLAY Sildenafil Cream, you can feel confident in what you’re using – every single time. This is the first clinical study of its kind to demonstrate that this specific topical formulation of sildenafil, DARE to PLAY Sildenafil Cream, can support genital blood flow and arousal in women.

Off-Label Use	Potential Risks	Medical Advice
Sildenafil for Female Libido	Cardiovascular side effects, interactions with other meds	Always consult a doctor before use
Non-approved supplements	Unknown composition, higher risk of adverse reactions	Use only if prescribed by a healthcare professional
DIY formulations	Dangerous, no clinical testing	Highly discouraged

Offering a non-hormonal option with a faster onset (10–15 minutes) and fewer side effects than oral medications, it represents a significant breakthrough for female sexual health. Daré’s proprietary formulation of Sildenafil Cream was evaluated in the RESPOND Study, the first-ever randomized, double-blind, placebo-controlled clinical trial for a topical treatment targeting Female Sexual Arousal Disorder (FSAD) submitted to the FDA. This Phase 2b trial included 200 premenopausal women experiencing symptoms of viagra tablet sex FSAD, such as reduced genital sensation and frustration during intimacy. Safety Profile: The side effect profile of DARE to PLAY Sildenafil Cream was similar to placebo (cream without sildenafil added), with no serious safety concerns reported. Study Results:Women using DARE to PLAY Sildenafil Cream experienced the following improvements, as measured by clinically validated and FDA-reviewed endpoints: Reduced feelings of sexual distress and interpersonal difficulties resulting from the sexual difficulties In the Phase 2b trial, after 12 weeks, women who used DARE to PLAY Sildenafil Cream reported statistically significant and clinically meaningful improvements in genital arousal sensation (warmth and tingling) compared to those who used placebo cream. On average, Arousal Sensation scores (measured by a patient-reported questionnaire) increased by over 2 points with DARE to PLAY Sildenafil Cream, compared to almost no change with placebo cream. Women who used DARE to PLAY Sildenafil Cream also showed improvement across other key areas of sexual function, including desire and orgasm.

The #1 Prescribed Treatment for frustrating Low Libido1

You will be notified in the coming months when ordering becomes available in your state. Ordering and payment will only occur once the product is available for pharmacy dispensing. Interest in DARE to PLAY has been strong. This period allows the manufacturer to complete planning and state licensing activities based on interest to ensure that once prescriptions can be filled, patients can receive DARE to PLAY reliably without interruption. DARE to PLAY Sildenafil Cream is a topical vaginal cream that works to do all of the following: Increases genital blood flow for enhanced sensitivity and responsiveness Improves natural lubrication, not just surface moisture Some women experience ongoing issues with physical sexual arousal, a condition known as female sexual arousal disorder (FSAD).

What causes low libido in women?

By delivering sildenafil (the active ingredient in Viagra®) directly to the genital tissues, this clinically studied cream helps restore pleasurable sexual experiences. Explore the clinical research published in the The Journal of Sexual Medicine and Obstetrics & Gynecology Journal. Unlike lubricants that simply mask symptoms, this female arousal cream is designed to support healthy blood flow to the clitoris and surrounding tissues, helping to enhance natural arousal sensations. DARE to PLAY Sildenafil Cream works by supporting the body’s natural arousal pathways, helping intimacy feel good again, physically and emotionally. Some women experience ongoing issues with physical sexual arousal, a condition known as female sexual arousal disorder (FSAD). Results shown are from a subset of 65 women in a 12-week clinical trial: 33 women who received Sildenafil Cream and 32 who received Placebo Cream.

Product	Dosage	Quantity + Bonus	Price
Viagra Professional	100mg	60 + 2 Pills	146.74€ 139.75€	Buy
Viagra Generic	100mg	270 + 10 Pills	270.47€ 257.59€	Buy
Viagra Original	100mg	120 + 8 Pills	470.39€ 447.99€	Buy
Viagra Generic	150mg	30 + 2 Pills	72.32€ 68.88€	Buy
Viagra Oral Jelly	100mg	10 Sachets	46.36€ 44.15€	Buy
Viagra Oral Jelly	100mg	30 + 5 Sachets	115.76€ 110.25€	Buy
Viagra Generic	100mg	360 + 10 Pills	330.21€ 314.49€	Buy
Viagra Super Active	100mg	270 + 30 Pills	390.61€ 372.01€	Buy
Viagra Generic	150mg	270 + 10 Pills	326.61€ 311.06€	Buy
Viagra Generic	200mg	90 + 6 Pills	170.79€ 162.66€	Buy
Viagra Generic	100mg	10 Pills	28.91€ 27.53€	Buy
Viagra Generic	50mg	120 + 6 Pills	129.64€ 123.47€	Buy
Viagra Generic	200mg	360 + 10 Pills	481.98€ 459.03€	Buy
Viagra Super Active	100mg	180 + 20 Pills	280.97€ 267.59€	Buy
Viagra Professional	100mg	270 + 6 Pills	456.97€ 435.21€	Buy
Viagra Generic	150mg	360 + 10 Pills	423.48€ 403.31€	Buy
Viagra Oral Jelly	100mg	63 + 7 Sachets	190.54€ 181.47€	Buy

The results were published in the Green Journal (Obstetrics & Gynecology), the official journal of the American College of Obstetricians and Gynecologists (ACOG) and highlighted on ACOG’s podcast The Green Room. Clinical trial results were also featured in The Journal of Sexual Medicine, the official journal of the International Society for the Study of Women’s Sexual Health. DARE to PLAY is the only sildenafil cream for women supported by published, peer-reviewed clinical data. It was studied in clinical trials that used clinically validated and FDA-reviewed endpoints to measure results. The cream is designed with a proprietary drug delivery system that helps sildenafil get into the vaginal and vulvar tissue, where it can act locally to increase blood flow. Other sildenafil creams on the market haven’t been proven to work–they have not been studied, shown to absorb properly or published in peer-reviewed research, and are often compounded without consistent quality standards. DARE to PLAY stands apart because it’s rigorously developed, science-backed, and held to the highest standards of quality and clinical evidence.

Real Science. Real Results.

DARE to PLAY Sildenafil Cream is a prescription-only medication. Here’s what the process looks like: The DARE Health Hub, powered by Medvantx Pharmacy, makes getting a prescription more convenient than ever. makes getting a prescription more convenient than ever. With telehealth prescribing, you can connect with a licensed healthcare provider without an in-person visit or a scheduled virtual appointment. Get started by visiting the DARE Health Hub, registering for an account, and completing the secure online questionnaire.

What is FSAD?

A licensed provider will review your responses and confirm via text message when your prescription is ready. Medvantx may call, text, or email you to verify information if needed. You will be notified in the coming months when DARE to PLAY is available to order** *Complimentary during the pre-fulfillment prescription period only. **We are currently in our pre-fulfillment prescription period. You can get a prescription for DARE to PLAY, even though you cannot place an order yet. Sildenafil (the active ingredient in Viagra®) has a long-established safety profile in men.

• HSDD (Hypoactive Sexual Desire Disorder) is a common condition characterized by low libido.
• FSAD (Female Sexual Arousal Disorder) involves difficulty achieving or maintaining arousal.
• Female Orgasmic Disorder is the persistent difficulty in achieving orgasm.
• Genitourinary Syndrome of Menopause (GSM) causes vaginal dryness and pain.
• Underlying medical conditions like diabetes or thyroid issues can affect sexual function.
• Medications, particularly antidepressants (SSRIs), are a common cause of low libido.
• Psychological causes include stress, anxiety, body image issues, or past trauma.

The topical formulation used in DARE to PLAY is designed to work locally (in the tissues that matter for sexual arousal) while minimizing how much of the drug enters the bloodstream.

Two Medicines

The cream uses special salts—tri-sodium citrate and potassium chloride—to helppush the active ingredient through theskin’s toughest layer. Normally, drugs can stick to the pink viagra skin’ssurface due to hydrogen bonding. Thehigh salt content in this cream helpsprevent that stickiness, allowingsildenafil to penetrate deeper into thetissue. The cream’s design includes bothwater-loving (hydrophilic) and oil-loving (hydrophobic) regions. This uniquestructure helps the cream interact withdifferent skin layers, ensuring the druggets where it needs to go.

Increased genital blood flow

The cream uses special salts—tri-sodium citrate and potassiumchloride—to help push the activeingredient through the skin’stoughest layer. Normally, drugs can stick to theskin’s surface due to hydrogenbonding. The high salt content inthis cream helps prevent thatstickiness, allowing sildenafil topenetrate deeper into the tissue. Thisunique structure helps the creaminteract with different skin layers,ensuring the drug gets where itneeds to go. May not penetrate into the epithelial tissue When it comes to your body and your health, consistency and safety aren’t optional – they are essential. DARE to PLAY has been evaluated in clinical studies and was well tolerated, with no significant safety concerns reported.

OUR PRE-FULFILLMENT PRESCRIPTION PERIOD HAS BEGUN.

Licensed healthcare providers can now write prescriptions for DARE to PLAY in all 50 states. Talk with your provider to see if DARE to PLAY is right for you. Bring this prescribing guide to your visit: Right now, you can get a prescription for DARE to PLAY — even though you cannot place an order yet. Sildenafil (the active ingredient in Viagra®) has been proven for decades to increase blood flow. DARE to PLAY Sildenafil Cream uses the same trusted ingredient in a targeted topical formula designed for the unique anatomy of the female genitals.

IN CLINICAL TRIALS1, WOMEN ON ADDYI EXPERIENCED:

It works by helping blood vessels in the clitoris and vulva relax and open, allowing increased blood flow – resulting in: Warmth, swelling, tingling/throbbing, and sensitivity in the genital area It has been shown to increase blood flow within 10-15 minutes after application. We also got busy with a full clinical study of 200 women experiencing symptoms of FSAD. Getting powerful ingredients like sildenafil through the skin isn’t easy – most drugs carry an electrical charge, and the skin’s outer layer (called the stratum corneum) is built to keep them out. That’s where DermaFlux™, a cutting-edge topical drug delivery system, comes in. This advanced cream technology helps deliver sildenafil deep into the tissues that matter for sexual arousal. The safety findings from the Phase 2b clinical study have been published and are available on the DARE to PLAY website.

• Online pharmacies like Superdrug Online Doctor offer private consultations.
• Boots Online Doctor provides a similar service for discreet access to treatments.
• LloydsPharmacy Online Doctor allows for private prescriptions following an assessment.
• The NHS provides treatment primarily for underlying causes like depression or menopause.
• Private clinics, such as The London Hormone Clinic, specialize in women's health.
• Costs for private prescriptions vary significantly, often £50-£100 per month.
• Always ensure any online provider is registered with the General Pharmaceutical Council.

If you experience difficulty with sexual arousal, including a lack of physical response or reduced genital sensitivity during sexual activity, you may benefit from DARE to PLAY. A conversation with a licensed healthcare provider can help determine whether it is appropriate for you. DARE to PLAY contains the same active ingredient as Viagra®, but it’s formulated specifically for women and applied directly where it’s needed. Unlike an oral pill, DARE to PLAY is a topical cream designed to work locally rather than systemically. Apply the cream with your finger 10 to 15 minutes before sexual activity up to once per day. Slowly squeeze out a length of cream about 2 ½ inches long for one 2-gram dose. Lying on your back, apply half the cream on and around the clitoris and the area around the vaginal opening, avoiding areas with hair.

• There is no true over-the-counter "female Viagra" available in UK pharmacies.
• Viagra (sildenafil) is licensed for men and is not approved for female sexual dysfunction.
• Some online sources may illegally sell prescription-only medications without consultation.
• Herbal libido supplements are available OTC but are not proven to be effective.
• Lubricants and moisturizers are widely available OTC without a prescription.
• Buying prescription medicine without a prescription is illegal and potentially dangerous.
• Always obtain medications through a legitimate consultation with a qualified prescriber.

Apply the rest of the cream just inside the vagina, rubbing the cream with a curved finger on the front wall of the vagina. Once applied, do not wipe off any of the cream until after sexual activity. In the Phase 2b clinical study, women did not use lubricants because the study was specifically designed to evaluate the impact of DARE to PLAY on the genital arousal response.